Gentamicin Impurity 9 CAS 287916-51-2 (free base)
| CAS No. | 287916-51-2 (free base) |
| Molecular Formula | C20H41N5O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 523.63 g/mol gives Gentamicin Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Gentamicin Impurity 9 (CAS 287916-51-2 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C20H41N5O7C2H4O2 and a molecular weight of 523.63 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, Gentamicin Impurity 9 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 523.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H41N5O7 5*C2H4O2 |
| Molecular Weight | 523.63 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 5 |
Related Gentamicin Standards
- Gentamicin A (CAS 13291-74-2)
- Gentamicin (CAS 1403-66-3)
- Gentamicin Sulfate EP Impurity E (CAS 2037-48-1)
- Gentamicin C1 (CAS 25876-10-2)
- Gentamicin Impurity 11 Pentaacetate Salt (CAS 25876-10-2(free base))
- Gentamicin Impurity 12 (CAS 25876-11-3)
- Gentamicin C1a (CAS 26098-04-4)
- Gentamicin B (CAS 36889-15-3)
Recommended Standards
- Sitagliptin Impurity 102 (CAS CATO-C4X-1144102)
- Ozagrel Impurity 31 (CAS CATO-C4X-197131)
- Dalilesen Impurity 8 (CAS 1505484-72-9)
- N-((Furan-2-carbonyl)oxy)-2-(methylamino)-2-oxoacetimidoyl cyanide (CAS 70792-03-9)
- [(1-ethyl-2,5-dimethyl-1h-pyrrol-3-yl)methyl](methyl)amine (CAS 1243606-13-4)
- 3,5-Difluoro-2-methyl-4-propoxyphenylboronic acid (CAS 2096339-21-6)
- 4-Chloro-3-hydroxyphenylboronic acid pinacol ester (CAS 1443151-85-6)
- 8-Methyl-8-azaspiro[4.5]Decan-2-amine (CAS 1503872-02-3)
- 2-((4-Chloro-6-((4-(naphthalen-2-yl)thiazol-2-yl)amino)pyrimidin-2-yl)thio)octanoic acid (CAS 1492060-44-2)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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